Duration and onset of action of high dose U‐500 regular insulin in severely insulin resistant subjects with type 2 diabetes

AIM: Although regular human U‐500 insulin (U‐500) is frequently used for insulin resistant type 2 diabetics, pharmacokinetic and pharmacodynamic studies in these individuals are lacking. We set out to determine the rate of onset, duration of action and total glucose lowering effect of two doses of U...

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Veröffentlicht in:Endocrinol Diabetes Metab
Hauptverfasser: Shrestha, Rupendra T., Kumar, Anjali F., Taddese, Abdisa, Khowaja, Ameer A., Moheet, Amir, Olawsky, Evan, Eberly, Lynn E., Seaquist, Elizabeth R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354819/
https://ncbi.nlm.nih.gov/pubmed/30815569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/edm2.41
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