Placental CpG methylation of HPA-axis genes is associated with cognitive impairment at age 10 among children born extremely preterm

A major component of the neuroendocrine system is the hypothalamus-pituitary adrenal (HPA) axis. HPA axis genes are also known to play a role in placental physiology. Thus, disruptions in the signaling of HPA axis-associated genes may adversely impact the placenta as well as fetal development, with...

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Pubblicato in:Horm Behav
Autori principali: Meakin, C.J., Martin, E.M., Santos, H.P., Mokrova, I., Kuban, K., O’Shea, T.M., Joseph, R.M., Smeester, L., Fry, R.C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354776/
https://ncbi.nlm.nih.gov/pubmed/29477804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2018.02.007
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