Mapping of γ/δ T cells reveals Vδ2+ T cells resistance to senescence

BACKGROUND: Immune adaptation with aging is a major of health outcomes. Studies in humans have mainly focus on αβ T cells while γδ T cells have been neglected despite their role in immunosurveillance. We investigated the impact of aging on γδ T cell subsets phenotypes, functions, senescence and thei...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Xu, Weili, Monaco, Gianni, Wong, Eleanor Huijin, Tan, Wilson Lek Wen, Kared, Hassen, Simoni, Yannick, Tan, Shu Wen, How, Wilson Zhi Yong, Tan, Crystal Tze Ying, Lee, Bernett Teck Kwong, Carbajo, Daniel, K.G., Srinivasan, Low, Ivy Chay Huang, Mok, Esther Wing Hei, Foo, Shihui, Lum, Josephine, Tey, Hong Liang, Tan, Wee Ping, Poidinger, Michael, Newell, Evan, Ng, Tze Pin, Foo, Roger, Akbar, Arne N., Fülöp, Tamas, Larbi, Anis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354624/
https://ncbi.nlm.nih.gov/pubmed/30528453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.053
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