Merkel Cell Polyoma Viral Load and Intratumoral CD8+ Lymphocyte Infiltration Predict Overall Survival in Patients With Merkel Cell Carcinoma

Introduction: Merkel cell carcinoma (MCC) is linked to the presence of clonally integrated Merkel cell polyomavirus (MCPyV) in up to 80% of the cases. The aim of the study was to determine the prognostic value of baseline MCPyV viral load and lymphocytic infiltration. Methods: MCPyV DNA prevalence,...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: von der Grün, Jens, Winkelmann, Ria, Meissner, Markus, Wieland, Ulrike, Silling, Steffi, Martin, Daniel, Fokas, Emmanouil, Rödel, Claus, Rödel, Franz, Balermpas, Panagiotis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354572/
https://ncbi.nlm.nih.gov/pubmed/30733932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00020
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