Daptomycin dosing in obese patients: analysis of the use of adjusted body weight versus actual body weight

BACKGROUND: Food and Drug Administration–approved daptomycin dosing uses actual body weight, despite limited dosing information for obese patients. Studies report alterations in daptomycin pharmacokinetics and creatine phosphokinase elevations associated with higher weight-based doses required for o...

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Detalhes bibliográficos
Publicado no:Ther Adv Infect Dis
Main Authors: Fox, Ashley N., Smith, Winter J., Kupiec, Katherine E., Harding, Stephanie J., Resman-Targoff, Beth H., Neely, Stephen B., White, Bryan P., Owens, Ryan E.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354309/
https://ncbi.nlm.nih.gov/pubmed/30728962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2049936118820230
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