Study the Longitudinal in vivo and Cross-Sectional ex vivo Brain Volume Difference for Disease Progression and Treatment Effect on Mouse Model of Tauopathy Using Automated MRI Structural Parcellation

Brain volume measurements extracted from structural MRI data sets are a widely accepted neuroimaging biomarker to study mouse models of neurodegeneration. Whether to acquire and analyze data in vivo or ex vivo is a crucial decision during the phase of experimental designs, as well as data analysis....

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Ma, Da, Holmes, Holly E., Cardoso, Manuel J., Modat, Marc, Harrison, Ian F., Powell, Nick M., O’Callaghan, James M., Ismail, Ozama, Johnson, Ross A., O’Neill, Michael J., Collins, Emily C., Beg, Mirza F., Popuri, Karteek, Lythgoe, Mark F., Ourselin, Sebastien
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354066/
https://ncbi.nlm.nih.gov/pubmed/30733665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00011
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