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A tetracycline-dependent ribozyme switch allows conditional induction of gene expression in Caenorhabditis elegans

The nematode Caenorhabditis elegans represents an important research model. Convenient methods for conditional induction of gene expression in this organism are not available. Here we describe tetracycline-dependent ribozymes as versatile RNA-based genetic switches in C. elegans. Ribozyme insertion...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wurmthaler, Lena A., Sack, Monika, Gense, Karina, Hartig, Jörg S., Gamerdinger, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353947/
https://ncbi.nlm.nih.gov/pubmed/30700719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08412-w
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