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Regulation of osteogenesis and osteoclastogenesis by zoledronic acid loaded on biodegradable magnesium-strontium alloy

Inhibiting osteoclasts and osteoclast precursors to reduce bone resorption is an important strategy to treat osteoclast-related diseases, such as peri-prosthetic osteolysis. In this study, our objective was to study the role of zoledronic acid (ZA), as a highly potent and nitrogen-containing bisphos...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Li, Mei, Wan, Peng, Wang, Weidan, Yang, Ke, Zhang, Yu, Han, Yong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353919/
https://ncbi.nlm.nih.gov/pubmed/30700724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37091-8
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