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Rho and Rac, but not ROCK, are required for secretion of human and mouse eosinophil-associated RNases

BACKGROUND: Eosinophil-associated RNases (EARs) are stored preformed in eosinophil cytoplasmic secretory granules and have a key role in eosinophil effector functions in host defense and inflammatory disorders. However, the secretion mechanisms of EARs are poorly understood. OBJECTIVE: Our study aim...

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Publicat a:Clin Exp Allergy
Autors principals: Shamri, Revital, Young, Kristen M., Weller, Peter F.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353669/
https://ncbi.nlm.nih.gov/pubmed/30295352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.13292
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