Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays

Rationale: The identification of causal variants responsible for disease associations from genome-wide association studies (GWASs) facilitates functional understanding of the biological mechanisms by which those genetic variants influence disease susceptibility. Objective: We aim to identify causal...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Castaldi, Peter J., Guo, Feng, Qiao, Dandi, Du, Fei, Naing, Zun Zar Chi, Li, Yan, Pham, Betty, Mikkelsen, Tarjei S., Cho, Michael H., Silverman, Edwin K., Zhou, Xiaobo
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353020/
https://ncbi.nlm.nih.gov/pubmed/30079747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201802-0337OC
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