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An experimental strategy unveiling exosomal microRNAs 486-5p, 181a-5p and 30d-5p from hypoxic tumour cells as circulating indicators of high-risk rectal cancer

Tumour hypoxia contributes to poor treatment outcome in locally advanced rectal cancer (LARC) and circulating extracellular vesicles (EVs) as potential biomarkers of tumour hypoxia and adverse prognosis have not been fully explored. We examined EV miRNAs from hypoxic colorectal cancer cell lines as...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Bjørnetrø, Tonje, Redalen, Kathrine Røe, Meltzer, Sebastian, Thusyanthan, Nirujah Sivarajah, Samiappan, Rampradeep, Jegerschöld, Caroline, Handeland, Karianne Risberg, Ree, Anne Hansen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352936/
https://ncbi.nlm.nih.gov/pubmed/30728923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2019.1567219
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