Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?

OBJECTIVES: Controlled immune responses rely on integrated crosstalk between cells and their microenvironment. We investigated whether targeting proinflammatory signals from the extracellular matrix that persist during pathological inflammation provides a viable strategy to treat rheumatoid arthriti...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Aungier, Susan R, Cartwright, Alison J, Schwenzer, Anja, Marshall, Jennifer L, Dyson, Michael R, Slavny, Peter, Parthiban, Kothai, Karatt-Vellatt, Aneesh, Sahbudin, Ilfita, Culbert, Eric, Hextall, Patrick, Clanchy, Felix IL, Williams, Richard, Marsden, Brian D, Raza, Karim, Filer, Andrew, Buckley, Christopher Dominic, McCafferty, John, Midwood, Kim S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Inflammatory Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352652/
https://ncbi.nlm.nih.gov/pubmed/30552174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-214294
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