Lysyl Oxidase Is a Key Player in BRAF/MAPK Pathway-Driven Thyroid Cancer Aggressiveness

Background: The BRAF(V600E) mutation is the most common somatic mutation in thyroid cancer. The mechanism associated with BRAF-mutant tumor aggressiveness remains unclear. Lysyl oxidase (LOX) is highly expressed in aggressive thyroid cancers, and involved in cancer metastasis. The objective was to d...

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Bibliografske podrobnosti
izdano v:Thyroid
Main Authors: Boufraqech, Myriem, Patel, Dhaval, Nilubol, Naris, Powers, Astin, King, Timothy, Shell, Jasmine, Lack, Justin, Zhang, Lisa, Gara, Sudheer Kumar, Gunda, Viswanath, Klubo-Gwiezdzinska, Joanna, Kumar, Suresh, Fagin, James, Knauf, Jeffrey, Parangi, Sareh, Venzon, David, Quezado, Martha, Kebebew, Electron
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc., publishers 2019
Teme:
Thyroid Cancer and Nodules
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352555/
https://ncbi.nlm.nih.gov/pubmed/30398411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2018.0424
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