RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage

OBJECTIVE: To uncover the microRNA (miRNA) interactome of the osteoarthritis (OA) pathophysiological process in the cartilage. METHODS: We performed RNA sequencing in 130 samples (n=35 and n=30 pairs for messenger RNA (mRNA) and miRNA, respectively) on macroscopically preserved and lesioned OA carti...

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Bibliografske podrobnosti
izdano v:Ann Rheum Dis
Main Authors: Coutinho de Almeida, Rodrigo, Ramos, Yolande F M, Mahfouz, Ahmed, den Hollander, Wouter, Lakenberg, Nico, Houtman, Evelyn, van Hoolwerff, Marcella, Suchiman, H Eka D, Rodríguez Ruiz, Alejandro, Slagboom, P Eline, Mei, Hailiang, Kiełbasa, Szymon M, Nelissen, Rob G H H, Reinders, Marcel, Meulenbelt, Ingrid
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2019
Teme:
Osteoarthritis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352405/
https://ncbi.nlm.nih.gov/pubmed/30504444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-213882
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