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Drosophila insulin‐like peptide dilp1 increases lifespan and glucagon‐like Akh expression epistatic to dilp2

Insulin/IGF signaling (IIS) regulates essential processes including development, metabolism, and aging. The Drosophila genome encodes eight insulin/IGF‐like peptide (dilp) paralogs, including tandem‐encoded dilp1 and dilp2. Many reports show that longevity is increased by manipulations that decrease...

詳細記述

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書誌詳細
出版年:Aging Cell
主要な著者: Post, Stephanie, Liao, Sifang, Yamamoto, Rochele, Veenstra, Jan A., Nässel, Dick R., Tatar, Marc
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351851/
https://ncbi.nlm.nih.gov/pubmed/30511458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12863
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