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Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

Induced pluripotent stem cells (IPSCs), with their unlimited regenerative capacity, carry the promise for tissue replacement to counter age‐related decline. However, attempts to realize in vivo iPSC have invariably resulted in the formation of teratomas. Partial reprogramming in prematurely aged mic...

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Bibliografiska uppgifter
I publikationen:Aging Cell
Huvudupphovsmän: Olova, Nelly, Simpson, Daniel J., Marioni, Riccardo E., Chandra, Tamir
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351826/
https://ncbi.nlm.nih.gov/pubmed/30450724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12877
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