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Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity
Induced pluripotent stem cells (IPSCs), with their unlimited regenerative capacity, carry the promise for tissue replacement to counter age‐related decline. However, attempts to realize in vivo iPSC have invariably resulted in the formation of teratomas. Partial reprogramming in prematurely aged mic...
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| Wydane w: | Aging Cell |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351826/ https://ncbi.nlm.nih.gov/pubmed/30450724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12877 |
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