Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients

Immunomodulatory drugs (IMIDs) are very effective in the treatment of multiple myeloma (MM). The description of their cereblon-mediated mechanism of action was a hallmark in MM research. Although the importance of IMID-induced degradation of cereblon-binding proteins is well described in vitro, the...

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Gepubliceerd in:Blood Cancer J
Hoofdauteurs: Kriegsmann, Katharina, Baertsch, Marc-Andrea, Awwad, Mohamed H. S., Merz, Maximilian, Hose, Dirk, Seckinger, Anja, Jauch, Anna, Becker, Natalia, Benner, Axel, Raab, Marc S., Hillengass, Jens, Bertsch, Uta, Dürig, Jan, Salwender, Hans Jürgen, Hänel, Mathias, Fenk, Roland, Munder, Markus, Weisel, Katja, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Hundemer, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351644/
https://ncbi.nlm.nih.gov/pubmed/30696815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0174-z
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