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DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions
A consistent gene set undergoes age-associated expression changes in the human cerebral cortex, and our Age-by-Disease Model posits that these changes contribute to psychiatric diseases by “pushing” the expression of disease-associated genes in disease-promoting directions. DNA methylation (DNAm) is...
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| Publicado no: | Transl Psychiatry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351569/ https://ncbi.nlm.nih.gov/pubmed/30696804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0372-2 |
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