Regulation of human brown adipose tissue by adenosine and A(2A) receptors – studies with [(15)O]H(2)O and [(11)C]TMSX PET/CT

PURPOSE: Brown adipose tissue (BAT) has emerged as a potential target to combat obesity and diabetes, but novel strategies to activate BAT are needed. Adenosine and A(2A) receptor (A2AR) agonism activate BAT in rodents, and endogenous adenosine is released locally in BAT as a by-product of noradrena...

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Publicat a:Eur J Nucl Med Mol Imaging
Autors principals: Lahesmaa, Minna, Oikonen, Vesa, Helin, Semi, Luoto, Pauliina, U Din, Mueez, Pfeifer, Alexander, Nuutila, Pirjo, Virtanen, Kirsi A.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351510/
https://ncbi.nlm.nih.gov/pubmed/30105585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-018-4120-2
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