Regulation of human brown adipose tissue by adenosine and A(2A) receptors – studies with [(15)O]H(2)O and [(11)C]TMSX PET/CT

PURPOSE: Brown adipose tissue (BAT) has emerged as a potential target to combat obesity and diabetes, but novel strategies to activate BAT are needed. Adenosine and A(2A) receptor (A2AR) agonism activate BAT in rodents, and endogenous adenosine is released locally in BAT as a by-product of noradrena...

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Publicado en:Eur J Nucl Med Mol Imaging
Autores principales: Lahesmaa, Minna, Oikonen, Vesa, Helin, Semi, Luoto, Pauliina, U Din, Mueez, Pfeifer, Alexander, Nuutila, Pirjo, Virtanen, Kirsi A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2018
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351510/
https://ncbi.nlm.nih.gov/pubmed/30105585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-018-4120-2
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