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Regulation of human brown adipose tissue by adenosine and A(2A) receptors – studies with [(15)O]H(2)O and [(11)C]TMSX PET/CT
PURPOSE: Brown adipose tissue (BAT) has emerged as a potential target to combat obesity and diabetes, but novel strategies to activate BAT are needed. Adenosine and A(2A) receptor (A2AR) agonism activate BAT in rodents, and endogenous adenosine is released locally in BAT as a by-product of noradrena...
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| Publicado no: | Eur J Nucl Med Mol Imaging |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351510/ https://ncbi.nlm.nih.gov/pubmed/30105585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-018-4120-2 |
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