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Neurobiological and Immunogenetic Aspects of Narcolepsy: Implications for Pharmacotherapy

Excessive daytime sleepiness (EDS) and cataplexy are common symptoms of narcolepsy, a sleep disorder associated with the loss of hypocretin/orexin (Hcrt) neurons. Although only a few drugs have received regulatory approval for narcolepsy to date, treatment involves diverse medications that affect mu...

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Detalhes bibliográficos
Publicado no:Sleep Med Rev
Main Authors: Szabo, Steven T., Thorpy, Michael J., Mayer, Geert, Peever, John H., Kilduff, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351197/
https://ncbi.nlm.nih.gov/pubmed/30503715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smrv.2018.09.006
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