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Sterol methyltransferase is required for optimal mitochondrial function and virulence in Leishmania major
Limited knowledge on the exact functions of ergostane-based sterols has hampered the application of sterol synthesis inhibitors against trypanosomatid parasites. Sterol methyltransferase (SMT) is directly involved in the synthesis of parasite specific C24-methylated sterols including ergosterol and...
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| Publicat a: | Mol Microbiol |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351164/ https://ncbi.nlm.nih.gov/pubmed/30260041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14139 |
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