Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication

The urothelium is an epithelia barrier lined by a luminal layer of binucleated, octoploid, superficial cells. Superficial cells are critical for production and transport of uroplakins, a family of proteins that assemble into a waterproof crystalline plaque that helps protect against infection and to...

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Pubblicato in:Cell Rep
Autori principali: Wang, Jia, Batourina, Ekatherina, Schneider, Kerry, Souza, Spenser, Swayne, Theresa, Liu, Chang, George, Christopher D., Tate, Tiffany, Dan, Hanbin, Wiessner, Gregory, Zhuravlev, Yelena, Canman, Julie C., Mysorekar, Indira U., Lee Mendelsohn, Cathy
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351079/
https://ncbi.nlm.nih.gov/pubmed/30304685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.042
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