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The Mechanism of Fluorescence Quenching of Protein Photosensitizers Based on miniSOG During Internalization of the HER2 Receptor

The protein photosensitizer miniSOG is a promising agent for photodynamic therapy. The genetically encoded phototoxins 4D5scFv-miniSOG and DARPin-miniSOG specifically bind to the HER2 receptor overexpressed on the surface of cancer cells and promote receptor-mediated internalization of HER2. We show...

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Pubblicato in:Acta Naturae
Autori principali: Kuzichkina, E. O., Shilova, O. N., Deyev, S. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: A.I. Gordeyev 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351032/
https://ncbi.nlm.nih.gov/pubmed/30713766
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