Expression and genotype-dependent catalytic activity of N-acetyltransferase 2 (NAT2) in human peripheral blood mononuclear cells and its modulation by Sirtuin 1

N-acetyltransferase 2 (NAT2) catalyzes the biotransformation of numerous arylamine and hydrazine drugs and carcinogens. Genetic polymorphisms of NAT2 modify drug efficacy and toxicity and susceptibility to diseases such as cancer and type 2 diabetes. Expression of NAT2 has been documented in the liv...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem Pharmacol
Egile Nagusiak: Salazar-González, Raúl A., Turiján-Espinoza, Eneida, Hein, David W., Milán-Segovia, Rosa C., Uresti-Rivera, Edith E., Portales-Pérez, Diana P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350916/
https://ncbi.nlm.nih.gov/pubmed/30149019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.08.034
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