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Natriuretic response to renal medullary endothelin B receptor activation is impaired in Dahl-salt sensitive rats on a high-fat diet

Renal medullary endothelin B receptors (ET(B)) mediate sodium excretion and blood pressure (BP) control. Several animal models of hypertension have impaired renal medullary ET(B) function. We found that 4-week high-caloric diet elevated systolic BP in Dahl-salt sensitive (DS) rats (126±2 vs. 143±3 m...

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Pubblicato in:Physiol Res
Autori principali: Kittikulsuth, Wararat, Hyndman, Kelly A., Pollock, Jennifer S., Pollock, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350911/
https://ncbi.nlm.nih.gov/pubmed/29947535
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