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Development of a peptide-based fluorescent probe for biological heme monitoring

Heme plays a vital role in cell biology and dysregulation of heme levels is implicated in a wide range of diseases. However, monitoring heme levels in biological systems is currently not straightforward. A short synthetic peptide probe containing 7-azatryptophan is shown to bind hemin in vitro with...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Newton, Laura D., Pascu, Sofia I., Tyrrell, Rex M., Eggleston, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350759/
https://ncbi.nlm.nih.gov/pubmed/30574967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob02290a
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