Implementing TMB measurement in clinical practice: considerations on assay requirements

Clinical evidence demonstrates that treatment with immune checkpoint inhibitor immunotherapy agents can have considerable benefit across multiple tumours. However, there is a need for the development of predictive biomarkers that identify patients who are most likely to respond to immunotherapy. Com...

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Bibliografski detalji
Izdano u:ESMO Open
Glavni autori: Büttner, Reinhard, Longshore, John W, López-Ríos, Fernando, Merkelbach-Bruse, Sabine, Normanno, Nicola, Rouleau, Etienne, Penault-Llorca, Frédérique
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2019
Teme:
Review
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350758/
https://ncbi.nlm.nih.gov/pubmed/30792906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2018-000442
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