Inhibition of Hedgehog signaling reprograms the dysfunctional immune microenvironment in breast cancer

Host responses to tumor cells include tumor suppressing or promoting mechanisms. We sought to detail the effect of Hedgehog (Hh) pathway inhibition on the composition of the mammary tumor immune portfolio. We hypothesized that Hh signaling mediates a crosstalk between breast cancer cells and macroph...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncoimmunology
Päätekijät: Hanna, Ann, Metge, Brandon J., Bailey, Sarah K., Chen, Dongquan, Chandrashekar, Darshan S., Varambally, Sooryanarayana, Samant, Rajeev S., Shevde, Lalita A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2018
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350695/
https://ncbi.nlm.nih.gov/pubmed/30723576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1548241
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