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Myelin basic protein charge isomers change macrophage polarization

PURPOSE: During a neuronal injury, a variety of immune cells infiltrate into the local microenvironment at the demyelination site. After the destruction of the intact myelin sheath, its major constituent myelin basic protein (MBP) dissociates from the plasma membrane and acts as a free ligand on the...

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Detalhes bibliográficos
Publicado no:J Inflamm Res
Main Authors: Tsitsilashvili, Elene, Sepashvili, Maia, Chikviladze, Marika, Shanshiashvili, Lali, Mikeladze, David
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350649/
https://ncbi.nlm.nih.gov/pubmed/30774410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S189570
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