Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis

Variations in N-acylethanolamines (NAE) levels are associated with obesity and metabolic comorbidities. Their role in the gut remains unclear. Therefore, we generated a mouse model of inducible intestinal epithelial cell (IEC)-specific deletion of N-acylphosphatidylethanolamine phospholipase D (NAPE...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Everard, Amandine, Plovier, Hubert, Rastelli, Marialetizia, Van Hul, Matthias, de Wouters d’Oplinter, Alice, Geurts, Lucie, Druart, Céline, Robine, Sylvie, Delzenne, Nathalie M., Muccioli, Giulio G., de Vos, Willem M., Luquet, Serge, Flamand, Nicolas, Di Marzo, Vincenzo, Cani, Patrice D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349942/
https://ncbi.nlm.nih.gov/pubmed/30692526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08051-7
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