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Cycles of protein condensation and discharge in nuclear organelles studied by fluorescence lifetime imaging

Nuclear organelles are viscous droplets, created by concentration-dependent condensation and liquid–liquid phase separation of soluble proteins. Nuclear organelles have been actively investigated for their role in cellular regulation and disease. However, these studies are highly challenging to perf...

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Publicado en:Nat Commun
Autores principales: Pliss, Artem, Levchenko, Svitlana M., Liu, Lixin, Peng, Xiao, Ohulchanskyy, Tymish Y., Roy, Indrajit, Kuzmin, Andrey N., Qu, Junle, Prasad, Paras N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349932/
https://ncbi.nlm.nih.gov/pubmed/30692529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08354-3
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