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Blockade of TNFα to Improve Human CD34+ Cell Repopulating Activity in Allogeneic Stem Cell Transplantation

Early release of TNFα after hematopoietic stem cell transplantation (HSCT) correlates with development of acute graft-vs.-host disease (GVHD). Here we tested the effect of TNFα and alloreactive T cells on early hematopoietic HSC genotype and function. Addition of TNFα (10 ng/ml) in liquid cultures w...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Senyuk, Vitalyi, Patel, Pritesh, Mahmud, Nadim, Rondelli, Damiano
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349828/
https://ncbi.nlm.nih.gov/pubmed/30723481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03186
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