Comparison of RNA-Seq and Microarray Gene Expression Platforms for the Toxicogenomic Evaluation of Liver From Short-Term Rat Toxicity Studies

Gene expression profiling is a useful tool to predict and interrogate mechanisms of toxicity. RNA-Seq technology has emerged as an attractive alternative to traditional microarray platforms for conducting transcriptional profiling. The objective of this work was to compare both transcriptomic platfo...

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Veröffentlicht in:Front Genet
Hauptverfasser: Rao, Mohan S., Van Vleet, Terry R., Ciurlionis, Rita, Buck, Wayne R., Mittelstadt, Scott W., Blomme, Eric A. G., Liguori, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349826/
https://ncbi.nlm.nih.gov/pubmed/30723492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00636
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