Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells

Rationale: Obesity is a risk factor for atherothrombosis and various cancers. However, the mechanisms are not yet completely clarified. Objectives: We aimed to verify whether the microparticles (MPs) released from thrombin-activated platelets differed in obese and non-obese women for number, size, a...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Grande, Rosalia, Dovizio, Melania, Marcone, Simone, Szklanna, Paulina B., Bruno, Annalisa, Ebhardt, H. Alexander, Cassidy, Hilary, Ní Áinle, Fionnuala, Caprodossi, Anna, Lanuti, Paola, Marchisio, Marco, Mingrone, Geltrude, Maguire, Patricia B., Patrignani, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349702/
https://ncbi.nlm.nih.gov/pubmed/30723407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00007
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