Conophylline inhibits high fat diet-induced non-alcoholic fatty liver disease in mice

Conophylline (CnP), a vinca alkaloid extracted from the leaves of the tropical plant Tabernaemontana divaricate, attenuates hepatic fibrosis in mice. We have previously shown that CnP inhibits non-alcoholic steatohepatitis (NASH) using a methionine-choline-deficient (MCD) diet-fed mouse model. Howev...

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Vydáno v:PLoS One
Hlavní autoři: Ohashi, Tomohiko, Nakade, Yukiomi, Ibusuki, Mayu, Kitano, Rena, Yamauchi, Taeko, Kimoto, Satoshi, Inoue, Tadahisa, Kobayashi, Yuji, Sumida, Yoshio, Ito, Kiyoaki, Nakao, Haruhisa, Umezawa, Kazuo, Yoneda, Masashi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349312/
https://ncbi.nlm.nih.gov/pubmed/30689650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210068
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