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Cooperative actions of Tbc1d1 and AS160/Tbc1d4 in GLUT4-trafficking activities

AS160 and Tbc1d1 are key Rab GTPase–activating proteins (RabGAPs) that mediate release of static GLUT4 in response to insulin or exercise-mimetic stimuli, respectively, but their cooperative regulation and its underlying mechanisms remain unclear. By employing GLUT4 nanometry with cell-based reconst...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hatakeyama, Hiroyasu, Morino, Taisuke, Ishii, Takuya, Kanzaki, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349102/
https://ncbi.nlm.nih.gov/pubmed/30482843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004614
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