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Nucleobase carbonyl groups are poor Mg(2+) inner-sphere binders but excellent monovalent ion binders—a critical PDB survey

Precise knowledge of Mg(2+) inner-sphere binding site properties is vital for understanding the structure and function of nucleic acid systems. Unfortunately, the PDB, which represents the main source of Mg(2+) binding sites, contains a substantial number of assignment issues that blur our understan...

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Publicat a:RNA
Autors principals: Leonarski, Filip, D'Ascenzo, Luigi, Auffinger, Pascal
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348993/
https://ncbi.nlm.nih.gov/pubmed/30409785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.068437.118
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