Droplet digital PCR as an alternative to FISH for MYCN amplification detection in human neuroblastoma FFPE samples

BACKGROUND: MYCN amplification directly correlates with the clinical course of neuroblastoma and poor patient survival, and serves as the most critical negative prognostic marker. Although fluorescence in situ hybridization (FISH) remains the gold standard for clinical diagnosis of MYCN status in ne...

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Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Somasundaram, Dinesh Babu, Aravindan, Sheeja, Yu, Zhongxin, Jayaraman, Muralidharan, Tran, Ngoc T. B., Li, Shibo, Herman, Terence S., Aravindan, Natarajan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348625/
https://ncbi.nlm.nih.gov/pubmed/30691436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5306-0
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