Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

Immunotherapy using either checkpoint blockade or the adoptive transfer of antitumor lymphocytes has shown effectiveness in treating cancers with high levels of somatic mutations—such as melanoma, smoking-induced lung cancers and bladder cancer—with little effect in other common epithelial cancers t...

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Udgivet i:Nat Med
Main Authors: Zacharakis, Nikolaos, Chinnasamy, Harshini, Black, Mary, Xu, Hui, Lu, Yong-Chen, Zheng, Zhili, Pasetto, Anna, Langhan, Michelle, Shelton, Thomas, Prickett, Todd, Gartner, Jared, Jia, Li, Trebska-McGowan, Katarzyna, Somerville, Robert P., Robbins, Paul F., Rosenberg, Steven A., Goff, Stephanie L., Feldman, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348479/
https://ncbi.nlm.nih.gov/pubmed/29867227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0040-8
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