Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs LINC01229 and MAFTRR

Genetic variation in the genomic regulatory landscape likely plays a crucial role in the pathology of disease. Non-coding variants associated with disease can influence the expression of long intergenic non-coding RNAs (lincRNAs), which in turn function in the control of protein-coding gene expressi...

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Vydáno v:Front Genet
Hlavní autoři: Leask, Megan, Dowdle, Amy, Salvesen, Hamish, Topless, Ruth, Fadason, Tayaza, Wei, Wenhua, Schierding, William, Marsman, Judith, Antony, Jisha, O’Sullivan, Justin M., Merriman, Tony R., Horsfield, Julia A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348267/
https://ncbi.nlm.nih.gov/pubmed/30719032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00733
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