TRAIL-Expressing Monocyte/Macrophages Are Critical for Reducing Inflammation and Atherosclerosis

Circulating tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) levels are reduced in patients with cardiovascular disease, and TRAIL gene deletion in mice exacerbates atherosclerosis and inflammation. How TRAIL protects against atherosclerosis and why levels are reduced in disease...

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Publicado en:iScience
Autores principales: Cartland, Siân P., Genner, Scott W., Martínez, Gonzalo J., Robertson, Stacy, Kockx, Maaike, Lin, Ruby CY., O'Sullivan, John F., Koay, Yen Chin, Manuneedhi Cholan, Pradeep, Kebede, Melkam A., Murphy, Andrew J., Masters, Seth, Bennett, Martin R., Jessup, Wendy, Kritharides, Leonard, Geczy, Carolyn, Patel, Sanjay, Kavurma, Mary M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348195/
https://ncbi.nlm.nih.gov/pubmed/30665196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.12.037
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