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A Dual-App Nucleoside Probe Provides Structural Insights into the Human Telomeric Overhang in Live Cells
Understanding the topology adopted by individual G-quadruplex (GQ)-forming sequences in vivo and targeting a specific GQ motif among others in the genome will have a profound impact on GQ-directed therapeutic strategies. However, this remains a major challenge as most of the tools poorly distinguish...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6348103/ https://ncbi.nlm.nih.gov/pubmed/30192541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08436 |
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