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Electrostatic interactions in the force-generating region of the human cardiac myosin modulate ADP dissociation from actomyosin

Human cardiac myosin has two isoforms, alpha and beta, sharing significant sequence similarity, but different in kinetics: ADP release from actomyosin is an order of magnitude faster in the alpha myosin isoform. Apparently, small differences in the sequence are responsible for distinct local inter-r...

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Detaylı Bibliyografya
Yayımlandı:Biochem Biophys Res Commun
Asıl Yazarlar: Gargey, Akhil, Ge, Jinghua, Tkachev, Yaroslav V., Nesmelov, Yuri E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348005/
https://ncbi.nlm.nih.gov/pubmed/30654937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.01.045
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