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Electrostatic interactions in the force-generating region of the human cardiac myosin modulate ADP dissociation from actomyosin
Human cardiac myosin has two isoforms, alpha and beta, sharing significant sequence similarity, but different in kinetics: ADP release from actomyosin is an order of magnitude faster in the alpha myosin isoform. Apparently, small differences in the sequence are responsible for distinct local inter-r...
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| Pubblicato in: | Biochem Biophys Res Commun |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6348005/ https://ncbi.nlm.nih.gov/pubmed/30654937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.01.045 |
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