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Multidrug-resistant plasmids repress chromosomally encoded T6SS to enable their dissemination

Acinetobacter baumannii (Ab) is a nosocomial pathogen with one of the highest rates of multidrug resistance (MDR). This is partially due to transmissible plasmids. Many Ab strains harbor a constitutively active type VI secretion system (T6SS) that is employed to kill nonkin bacteria. T6SS and plasmi...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Di Venanzio, Gisela, Moon, Ki Hwan, Weber, Brent S., Lopez, Juvenal, Ly, Pek Man, Potter, Robert F., Dantas, Gautam, Feldman, Mario F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347727/
https://ncbi.nlm.nih.gov/pubmed/30626645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812557116
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