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Social status alters chromatin accessibility and the gene regulatory response to glucocorticoid stimulation in rhesus macaques

Low social status is an important predictor of disease susceptibility and mortality risk in humans and other social mammals. These effects are thought to stem in part from dysregulation of the glucocorticoid (GC)-mediated stress response. However, the molecular mechanisms that connect low social sta...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Snyder-Mackler, Noah, Sanz, Joaquín, Kohn, Jordan N., Voyles, Tawni, Pique-Regi, Roger, Wilson, Mark E., Barreiro, Luis B., Tung, Jenny
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347725/
https://ncbi.nlm.nih.gov/pubmed/30538209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811758115
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