Amino acid permeases in Cryptococcus neoformans are required for high temperature growth and virulence; and are regulated by Ras signaling

Cryptococcosis is an Invasive Fungal Infection (IFI) caused by Cryptococcus neoformans, mainly in immunocompromised patients. Therapeutic failure due to pathogen drug resistance, treatment inconstancy and few antifungal options is a problem. The study of amino acid biosynthesis and uptake represents...

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Veröffentlicht in:PLoS One
Hauptverfasser: Calvete, Crislaine Lambiase, Martho, Kevin Felipe, Felizardo, Gabrielle, Paes, Alexandre, Nunes, João Miguel, Ferreira, Camila Oliveira, Vallim, Marcelo A., Pascon, Renata C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347259/
https://ncbi.nlm.nih.gov/pubmed/30682168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211393
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