Iba-1(-)/CD68(+) microglia are a prominent feature of age-associated deep subcortical white matter lesions

Deep subcortical lesions (DSCL) of the brain, are present in ~60% of the ageing population, and are linked to cognitive decline and depression. DSCL are associated with demyelination, blood brain barrier (BBB) dysfunction, and microgliosis. Microglia are the main immune cell of the brain. Under phys...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Waller, Rachel, Baxter, Lynne, Fillingham, Daniel J., Coelho, Santiago, Pozo, Jose M., Mozumder, Meghdoot, Frangi, Alejandro F., Ince, Paul G., Simpson, Julie E., Highley, J. Robin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347230/
https://ncbi.nlm.nih.gov/pubmed/30682074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210888
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