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Rab5-independent activation and function of yeast Rab7-like protein, Ypt7p, in the AP-3 pathway

The small GTPases, Rab5 and Rab7, are key regulators at multiple stages of the endocytic/endolysosomal pathway, including fusion and maturation of endosomes. In yeast, Vps21p (Rab5 homolog) recruits a GEF for Rab7 and activates the downstream Ypt7p (Rab7 homolog) on endosomal membrane. Although the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Shimamura, Hiroki, Nagano, Makoto, Nakajima, Keita, Toshima, Junko Y., Toshima, Jiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347229/
https://ncbi.nlm.nih.gov/pubmed/30682048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210223
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