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Rab5-independent activation and function of yeast Rab7-like protein, Ypt7p, in the AP-3 pathway
The small GTPases, Rab5 and Rab7, are key regulators at multiple stages of the endocytic/endolysosomal pathway, including fusion and maturation of endosomes. In yeast, Vps21p (Rab5 homolog) recruits a GEF for Rab7 and activates the downstream Ypt7p (Rab7 homolog) on endosomal membrane. Although the...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6347229/ https://ncbi.nlm.nih.gov/pubmed/30682048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210223 |
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