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Potential off-target effects of beta-blockers on gut hormone receptors: In silico study including GUT-DOCK—A web service for small-molecule docking

The prolonged use of many currently available drugs results in the severe side effect of the disruption of glucose metabolism leading to type 2 diabetes mellitus (T2DM. Gut hormone receptors including glucagon receptor (GCGR) and the incretin hormone receptors: glucagon-like peptide 1 receptor (GLP1...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Pasznik, Pawel, Rutkowska, Ewelina, Niewieczerzal, Szymon, Cielecka-Piontek, Judyta, Latek, Dorota
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347188/
https://ncbi.nlm.nih.gov/pubmed/30682072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210705
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