The Ability of Lytic Staphylococcal Podovirus vB_SauP_phiAGO1.3 to Coexist in Equilibrium With Its Host Facilitates the Selection of Host Mutants of Attenuated Virulence but Does Not Preclude the Phage Antistaphylococcal Activity in a Nematode Infection Model

Phage vB_SauP_phiAGO1.3 (phiAGO1.3) is a polyvalent Staphylococcus lytic podovirus with a 17.6-kb genome (Gozdek et al., 2018). It can infect most of the Staphylococcus aureus human isolates of dominant clonal complexes. We show that a major factor contributing to the wide host range of phiAGO1.3 is...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Głowacka-Rutkowska, Aleksandra, Gozdek, Agnieszka, Empel, Joanna, Gawor, Jan, Żuchniewicz, Karolina, Kozińska, Aleksandra, Dębski, Janusz, Gromadka, Robert, Łobocka, Małgorzata
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346686/
https://ncbi.nlm.nih.gov/pubmed/30713528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03227
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